Crumbs2 mediates ventricular layer remodelling to form the spinal cord central canal.

Crumbs2 mediates ventricular layer remodelling to form the spinal cord central canal.

In the spinal cord, the central canal forms through a poorly understood process termed dorsal collapse that involves attrition and remodelling of pseudostratified ventricular layer (VL) cells. Here, we use mouse and chick models to show that dorsal ventricular layer (dVL) cells adjacent to dorsal mi...

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Bibliographic Details
Main Authors: Christine M Tait, Kavitha Chinnaiya, Elizabeth Manning, Mariyam Murtaza, John-Paul Ashton, Nicholas Furley, Chris J Hill, C Henrique Alves, Jan Wijnholds, Kai S Erdmann, Andrew Furley, Penny Rashbass, Raman M Das, Kate G Storey, Marysia Placzek
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-03-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3000470

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https://doi.org/10.1371/journal.pbio.3000470

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