Genome-wide analysis of DNA replication timing in single cells: Yes! We’re all individuals

Abstract Recent studies have accomplished the extraordinary feat of measuring the exact status of DNA replication in individual cells. We outline how these studies have revealed surprising uniformity in how cells replicate their DNA, and consider the implications of this remarkable technological adv...

Full description

Bibliographic Details
Main Authors: Anne D. Donaldson, Conrad A. Nieduszynski
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Genome Biology
Online Access:http://link.springer.com/article/10.1186/s13059-019-1719-y