Citrus-derived auraptene stimulates angiogenesis by activating the Erk- and PI3K/Akt/eNOS-dependent signaling pathways in human umbilical vein endothelial cells

Auraptene is a citrus-derived natural monoterpene that has been shown to exert anti-cancer, anti-bacterial, anti-inflammatory, and antioxidant roles. Since little is known about other biological functions of auraptene, we examined the efficacy of auraptene for stimulating angiogenesis in human umbil...

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Main Authors: Shuaiyu Wang, Yeo Cho Yoon, Mi-Jeong Sung, Jin-Taek Hwang, Haeng-Jeon Hur, Hyun-Jin Kim, Hye Jeong Yang, Myung-Sunny Kim, Dae Young Kwon, Jae-Ho Park
Format: Article
Language:English
Published: Elsevier 2012-10-01
Series:Journal of Functional Foods
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464612001028