New Insights into Development of Transglutaminase 2 Inhibitors as Pharmaceutical Lead Compounds
Transglutaminase 2 (EC 2.3.2.13; TG2 or TGase 2) plays important roles in the pathogenesis of many diseases, including cancers, neurodegeneration, and inflammatory disorders. Under normal conditions, however, mice lacking TGase 2 exhibit no obvious abnormal phenotype. TGase 2 expression is induced b...
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| Format: | Article |
| Language: | English |
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MDPI AG
2018-10-01
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| Series: | Medical Sciences |
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| Online Access: | http://www.mdpi.com/2076-3271/6/4/87 |