Nanobody Nb6 fused with porcine IgG Fc as the delivering tag to inhibit porcine reproductive and respiratory syndrome virus replication in porcine alveolar macrophages

Nanobody Nb6 fused with porcine IgG Fc as the delivering tag to inhibit porcine reproductive and respiratory syndrome virus replication in porcine alveolar macrophages

Abstract Porcine reproductive and respiratory syndrome virus (PRRSV) is a highly contagious virus that has led to enormous economic loss worldwide because of ineffective prevention and treatment. In view of their minimized size, high target specificity and affinity, nanobodies have been extensively...

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Bibliographic Details
Main Authors: Lu Zhang, Lizhen Wang, Shuaishuai Cao, Huanhuan Lv, Jingjing Huang, Guixi Zhang, Kaissar Tabynov, Qin Zhao, En-Min Zhou
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Veterinary Research
Subjects:
nanobody
nanobody-pFc
PRRSV
permissive cell targeting
antiviral agents
Online Access:https://doi.org/10.1186/s13567-020-00868-9

Internet

https://doi.org/10.1186/s13567-020-00868-9

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