Involvement of calpains in adult neurogenesis: implications for stroke

Calpains are ubiquitous proteases involved in cell proliferation, adhesion and motility. In the brain, calpains have been associated with neuronal damage in both acute and neurodegenerative disorders, but their physiological function in the nervous system remains elusive. During brain ischemia, ther...

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Bibliographic Details
Main Authors: Vanessa Mendes Machado, Maria Inês Morte, Bruno Pereira Carreira, Maria Manuela Azevedo, Jiro eTakano, Nobuhisa eIwata, Takaomi C Saido, Hannelore eAsmussen, Alan Rick Horwitz, Caetana Monteiro Carvalho, Inês Maria Araújo
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-02-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00022/full