P2X7 receptor and caspase 1 activation are central to airway inflammation observed after exposure to tobacco smoke.

P2X7 receptor and caspase 1 activation are central to airway inflammation observed after exposure to tobacco smoke.

Chronic Obstructive Pulmonary Disease (COPD) is a cigarette smoke (CS)-driven inflammatory airway disease with an increasing global prevalence. Currently there is no effective medication to stop the relentless progression of this disease. It has recently been shown that an activator of the P2X7/infl...

Full description

Bibliographic Details
Main Authors: Suffwan Eltom, Christopher S Stevenson, Joseph Rastrick, Nicole Dale, Kristof Raemdonck, Sissie Wong, Matthew C Catley, Maria G Belvisi, Mark A Birrell
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3167831?pdf=render

Internet

http://europepmc.org/articles/PMC3167831?pdf=render

Similar Items