Serum response factor is required for cell contact maintenance but dispensable for proliferation in visceral yolk sac endothelium

<p>Abstract</p> <p>Background</p> <p>Endothelial-specific knockout of the transcription factor serum response factor (SRF) results in embryonic lethality by mid-gestation. The associated phenotype exhibits vascular failure in embryos as well as visceral yolk sac (VYS) t...

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Bibliographic Details
Main Authors: Misra Ravi P, Holtz Mary L
Format: Article
Language:English
Published: BMC 2011-03-01
Series:BMC Developmental Biology
Online Access:http://www.biomedcentral.com/1471-213X/11/18