Simultaneous pharmacokinetic assessment of cefadroxil and clavulanic acid in human plasma by LCâMS and its application to bioequivalence studies

A simple, rapid and selective liquid chromatographyâatmospheric pressure chemical ionizationâmass spectrometry (LCâAPCIâMS) assay method has been developed and fully validated for the simultaneous quantification of cefadroxil (CF) and clavulanic acid (CA) in human plasma. Analytes and internal stand...

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Bibliographic Details
Main Authors: Janaki Sankarachari Krishnan Nagarajan, Chandran Sathish Vimal, Renjith George, Anil Dubala
Format: Article
Language:English
Published: Elsevier 2013-08-01
Series:Journal of Pharmaceutical Analysis
Online Access:http://www.sciencedirect.com/science/article/pii/S2095177913000142