Biological Activities and ADMET-Related Properties of Novel Set of Cinnamanilides

Biological Activities and ADMET-Related Properties of Novel Set of Cinnamanilides

A series of nineteen novel ring-substituted <i>N</i>-arylcinnamanilides was synthesized and characterized. All investigated compounds were tested against <i>Staphylococcus aureus</i> as the reference strain, two clinical isolates of methicillin-resistant <i>S. aureus<...

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Bibliographic Details
Main Authors: Jiri Kos, Andrzej Bak, Violetta Kozik, Timotej Jankech, Tomas Strharsky, Aleksandra Swietlicka, Hana Michnova, Jan Hosek, Adam Smolinski, Michal Oravec, Ferdinand Devinsky, Milan Hutta, Josef Jampilek
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Molecules
Subjects:
cinnamamides
synthesis
antistaphylococcal activity
MTT assay
cytotoxicity
lipophilicity
Online Access:https://www.mdpi.com/1420-3049/25/18/4121

Internet

https://www.mdpi.com/1420-3049/25/18/4121

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