Absolute quantification of serum microRNA-122 and its correlation with liver inflammation grade and serum alanine aminotransferase in chronic hepatitis C patients

Objectives: MicroRNA-122 has been shown to be crucial for efficient HCV RNA replication in vitro. Pretreatment intrahepatic microRNA-122 levels in chronic hepatitis C (CHC) patients have been associated with the outcomes of interferon therapy. Here, we determined microRNA-122 serum levels in CHC pat...

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Bibliographic Details
Main Authors: Jiang-hua Wang, Dong Jiang, Hui-yng Rao, Jing-min Zhao, Yu Wang, Lai Wei
Format: Article
Language:English
Published: Elsevier 2015-01-01
Series:International Journal of Infectious Diseases
Subjects:
ALT
Online Access:http://www.sciencedirect.com/science/article/pii/S1201971214016865