APOE4 moderates effects of cortical iron on synchronized default mode network activity in cognitively healthy old‐aged adults

APOE4 moderates effects of cortical iron on synchronized default mode network activity in cognitively healthy old‐aged adults

Abstract Introduction Apolipoprotein E ε4 (APOE4)–related genetic risk for sporadic Alzheimer's disease is associated with an early impairment of cognitive brain networks. The current study determines relationships between APOE4 carrier status, cortical iron, and cortical network‐functionality....

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Bibliographic Details
Main Authors: Sonja M. Kagerer, Jiri M. G. vanBergen, Xu Li, Frances C. Quevenco, Anton F. Gietl, Sandro Studer, Valerie Treyer, Rafael Meyer, Philipp A. Kaufmann, Roger M. Nitsch, Peter C. M. vanZijl, Christoph Hock, Paul G. Unschuld
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
Subjects:
APOE4
DMN
flutemetamol
fMRI
gradient echo
ICA
Online Access:https://doi.org/10.1002/dad2.12002

Internet

https://doi.org/10.1002/dad2.12002

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