A novel measure of chromosome instability can account for prognostic difference in multiple myeloma.

Multiple myeloma (MM) is characterized by complex genetic abnormalities whose complexity signifies varying degree of chromosomal instability (CIN). In this study, we introduced a novel CIN measure, chromosome instability genome event count (CINGEC), which considered both copy number aberrations and...

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Bibliographic Details
Main Authors: Tae-Hoon Chung, George Mulligan, Rafael Fonseca, Wee Joo Chng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23840451/pdf/?tool=EBI