Lysosomes and α-synuclein form a dangerous duet leading to neuronal cell death
Neurodegenerative diseases are (i) characterized by a selective neuronal vulnerability to degeneration in specific brain regions and (ii) likely to be caused by disease-specific protein misfolding. Parkinson’s disease (PD) is characterized by the presence of intraneuronal proteinacious cytoplasmic i...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2014-08-01
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| Series: | Frontiers in Neuroanatomy |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fnana.2014.00083/full |