NF-κB-Dependent IFIT3 Induction by HBx Promotes Hepatitis B Virus Replication

NF-κB-Dependent IFIT3 Induction by HBx Promotes Hepatitis B Virus Replication

Therapeutic administration of type I IFN (IFN-I) is a common treatment option for individuals suffering from hepatitis B virus (HBV) infection. IFN-I therapy, however, has a relatively low response rate in HBV-infected patients and can induce serious side-effects, limiting its clinical efficacy. The...

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Bibliographic Details
Main Authors: Fengchao Xu, Hongxiao Song, Beiying An, Qingfei Xiao, Genhong Cheng, Guangyun Tan
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Microbiology
Subjects:
IFIT3
NF-κB
HBx
HBV
interferon
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.02382/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2019.02382/full

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