Suggestive evidence of associations between liver X receptor β polymorphisms with type 2 diabetes mellitus and obesity in three cohort studies: HUNT2 (Norway), MONICA (France) and HELENA (Europe)

<p>Abstract</p> <p>Background</p> <p>The liver X receptors (LXR) α and β regulate lipid and carbohydrate homeostasis and inflammation. <it>Lxrβ</it><sup><it>-/- </it></sup>mice are glucose intolerant and at the same time lean. We aime...

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Main Authors: Dallongeville Jean, Ruiz Jonatan R, Widhalm Kurt, Valtueña Jara, Romeo Javier, Lien Sigbjorn, Amouyel Philippe, Ferrières Jean, Holven Kirsten B, Berg Paul R, Retterstol Kjetil, Legry Vanessa, Solaas Karianne, Tonstad Serena, Rootwelt Helge, Halvorsen Bente, Nenseter Marit S, Birkeland Kare I, Thorsby Per M, Meirhaeghe Aline, Nebb Hilde I
Format: Article
Language:English
Published: BMC 2010-10-01
Series:BMC Medical Genetics
Online Access:http://www.biomedcentral.com/1471-2350/11/144