Preterm Birth Is Associated With Immune Dysregulation Which Persists in Infants Exposed to Histologic Chorioamnionitis

Preterm Birth Is Associated With Immune Dysregulation Which Persists in Infants Exposed to Histologic Chorioamnionitis

IntroductionPreterm infants are at increased risk of exposure to histologic chorioamnionitis (HCA) when compared to term-born controls, and this is associated with several neonatal morbidities involving brain, lungs and gut. Preterm infants could benefit from immunomodulatory therapies in the perina...

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Bibliographic Details
Main Authors: Gemma Sullivan, Paola Galdi, Nis Borbye-Lorenzen, David Q. Stoye, Gillian J. Lamb, Margaret J. Evans, Kristin Skogstrand, Siddharthan Chandran, James P. Boardman
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Immunology
Subjects:
complement
cytokine
fetal inflammatory response
inflammation
immunity
interleukin
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.722489/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.722489/full

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