Crystal structure of thioredoxin 1 from Cryptococcus neoformans at 1.8 Å resolution shows unexpected plasticity of the loop preceding the catalytic site

An elevated prevalence of cryptococcal infection is a tendency in low-income countries and constitutes a global public health problem due to factors such as the limited efficacy of antifungal therapy and the AIDS/transplant immunocompromised patients. The fungus Cryptococcus neoformans, implicated i...

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Bibliographic Details
Main Authors: Claudia Patricia Bravo-Chaucanés, Ana Karina Rodrigues Abadio, Érika Seki Kioshima, Maria Sueli Soares Felipe, João Alexandre Ribeiro Gonçalves Barbosa
Format: Article
Language:English
Published: Elsevier 2020-03-01
Series:Biochemistry and Biophysics Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580819301554