Disruption of nucleocytoplasmic trafficking of cyclin D1 and topoisomerase II by sanguinarine
<p>Abstract</p> <p>Background</p> <p>The quaternary isoquinoline alkaloid sanguinarine is receiving increasing attention as a potential chemotherapeutic agent in the treatment of cancer. Previous studies have shown that this DNA-binding phytochemical can arrest a number...
Main Authors: | Perkins Edward, Lamont Genelle, Holy Jon |
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Format: | Article |
Language: | English |
Published: |
BMC
2006-03-01
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Series: | BMC Cell Biology |
Online Access: | http://www.biomedcentral.com/1471-2121/7/13 |
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