Effective transcription factor binding site prediction using a combination of optimization, a genetic algorithm and discriminant analysis to capture distant interactions

<p>Abstract</p> <p>Background</p> <p>Reliable transcription factor binding site (TFBS) prediction methods are essential for computer annotation of large amount of genome sequence data. However, current methods to predict TFBSs are hampered by the high false-positive rat...

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Bibliographic Details
Main Authors: Merkulova Tatyana I, Turnaev Igor I, Ananko Elena A, Ignatieva Elena V, Levitsky Victor G, Kolchanov Nikolay A, Hodgman TC
Format: Article
Language:English
Published: BMC 2007-12-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/8/481