Multiple adverse drug reactions during all-trans retinoic acid treatment for acute promyelocytic leukemia: differentiation syndrome, bradycardia, intestinal necrosis

All-trans retinoic acid (ATRA) induces complete remission in a high proportion of acute promyelocytic leukemia (APL). Nevertheless it is be associated with adverse drug reactions that might be life-threatening including differentiation syndrome, myocarditis, myositis, Sweet’s syndrome and ulcers. We...

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Bibliographic Details
Main Authors: Valeria Ferla, Mariarita Sciumé, Umberto Gianelli2, Luca Baldini, Nicola Stefano Fracchiolla
Format: Article
Language:English
Published: Open Exploration Publishing Inc. 2020-04-01
Series:Exploration of Targeted Anti-tumor Therapy
Subjects:
Online Access:https://www.explorationpub.com/Journals/etat/Article/10027