Role of Palmitoylation of Postsynaptic Proteins in Promoting Synaptic Plasticity

Many postsynaptic proteins undergo palmitoylation, the reversible attachment of the fatty acid palmitate to cysteine residues, which influences trafficking, localization, and protein interaction dynamics. Both palmitoylation by palmitoyl acyl transferases (PAT) and depalmitoylation by palmitoyl-prot...

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Bibliographic Details
Main Authors: Lucas Matt, Karam Kim, Dhrubajyoti Chowdhury, Johannes W. Hell
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Molecular Neuroscience
Subjects:
LTP
LTD
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2019.00008/full