The Role of the COP9 Signalosome and Neddylation in DNA Damage Signaling and Repair
The maintenance of genomic integrity is an important process in organisms as failure to sense and repair damaged DNA can result in a variety of diseases. Eukaryotic cells have developed complex DNA repair response (DDR) mechanisms to accurately sense and repair damaged DNA. Post-translational modifi...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2015-09-01
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Series: | Biomolecules |
Subjects: | |
Online Access: | http://www.mdpi.com/2218-273X/5/4/2388 |