Cardiac hypertrophy or failure? - A systematic evaluation of the transverse aortic constriction model in C57BL/6NTac and C57BL/6J substrains

Cardiac hypertrophy or failure? - A systematic evaluation of the transverse aortic constriction model in C57BL/6NTac and C57BL/6J substrains

Background: The mouse model of transverse aortic constriction (TAC) has been widely used as a cardiac stress in the investigation of the molecular mechanisms of cardiac hypertrophy. Recently, the International Knockout Mouse Consortium has selected the C57BL/6NTac (BL/6N) mouse strain to generate nu...

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Bibliographic Details
Main Authors: Min Zi, Nicholas Stafford, Sukhpal Prehar, Florence Baudoin, Delvac Oceandy, Xin Wang, Thuy Bui, Mohamed Shaheen, Ludwig Neyses, Elizabeth J. Cartwright
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:Current Research in Physiology
Subjects:
C57BL/6
Cardiac hypertrophy
Heart failure
Transverse aortic constriction (TAC)
Online Access:http://www.sciencedirect.com/science/article/pii/S266594411930001X

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http://www.sciencedirect.com/science/article/pii/S266594411930001X

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