Follicular CD4 T Cells Tutor CD8 Early Memory Precursors: An Initiatory Journey to the Frontier of B Cell Territory

Summary: The early events of CD8 memory generation remain largely unknown. Here we report that as early as 2 days after antigen priming, very early memory precursors can be identified by their expression of the chemokine receptor CXCR5. These early precursors, which have an effector phenotype, expan...

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Bibliographic Details
Main Authors: Marie-Ghislaine de Goër de Herve, Maïsa Abdoh, Salma Jaafoura, Deniz Durali, Yassine Taoufik
Format: Article
Language:English
Published: Elsevier 2019-10-01
Series:iScience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004219303499