A Candidate Gene Approach to ANCA-Associated Vasculitis Reveals Links to the C3 and CTLA-4 Genes but not to the IL1-Ra And Fcγ-RIIa Genes

A Candidate Gene Approach to ANCA-Associated Vasculitis Reveals Links to the C3 and CTLA-4 Genes but not to the IL1-Ra And Fcγ-RIIa Genes

Background/Aims: The aim of the study is to search for associations between Antineutrophil cytoplasm antibody (ANCA)-associated vasculitis (AAV) and polymorphisms in the genes of four key molecules possibly involved in different pathogenic pathways; complement C3, CTLA-4, Fcγ-RIIa and IL1-R...

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Bibliographic Details
Main Authors: Ulf Persson, Birgitta Gullstrand, Åsa Pettersson, Gunnar Sturfelt, Lennart Truedsson, Mårten Segelmark
Format: Article
Language:English
Published: Karger Publishers 2013-12-01
Series:Kidney & Blood Pressure Research
Subjects:
ANCA
Genetics
Granulomatosis with polyangiitis
Microscopic polyangiitis
Wegener’s granulomatosis
Online Access:http://www.karger.com/Article/FullText/355744

Internet

http://www.karger.com/Article/FullText/355744

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