An intriguing shift occurs in the novel protein phosphatase 1 binding partner, TCTEX1D4: evidence of positive selection in a pika model.

T-complex testis expressed protein 1 domain containing 4 (TCTEX1D4) contains the canonical phosphoprotein phosphatase 1 (PPP1) binding motif, composed by the amino acid sequence RVSF. We identified and validated the binding of TCTEX1D4 to PPP1 and demonstrated that indeed this protein is a novel PPP...

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Main Authors: Luís Korrodi-Gregório, Ana Margarida Lopes, Sara L C Esteves, Sandra Afonso, Ana Lemos de Matos, Andrey A Lissovsky, Odete A B da Cruz e Silva, Edgar F da Cruz e Silva, Pedro José Esteves, Margarida Fardilha
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3795061?pdf=render