Allelic Interaction between <em>CRELD1</em> and <em>VEGFA</em> in the Pathogenesis of Cardiac Atrioventricular Septal Defects
Atrioventricular septal defects (AVSD) are highly heritable, clinically significant congenital heart malformations. Genetic and environmental modifiers of risk are thought to work in unknown combinations to cause AVSD. Approximately 5–10% of simplex AVSD cases carry a missense mutation in <em>...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
AIMS Press
2014-03-01
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| Series: | AIMS Genetics |
| Subjects: | |
| Online Access: | http://www.aimspress.com/Genetics/article/58/fulltext.html |