Allelic Interaction between <em>CRELD1</em> and <em>VEGFA</em> in the Pathogenesis of Cardiac Atrioventricular Septal Defects

Allelic Interaction between <em>CRELD1</em> and <em>VEGFA</em> in the Pathogenesis of Cardiac Atrioventricular Septal Defects

Atrioventricular septal defects (AVSD) are highly heritable, clinically significant congenital heart malformations. Genetic and environmental modifiers of risk are thought to work in unknown combinations to cause AVSD. Approximately 5–10% of simplex AVSD cases carry a missense mutation in <em>...

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Bibliographic Details
Main Authors: Jennifer K. Redig, Gameil T. Fouad, Darcie Babcock, Benjamin Reshey, Eleanor Feingold, Roger H. Reeves, Cheryl L. Maslen
Format: Article
Language:English
Published: AIMS Press 2014-03-01
Series:AIMS Genetics
Subjects:
congenital heart disease
genetic modifier
Online Access:http://www.aimspress.com/Genetics/article/58/fulltext.html

Internet

http://www.aimspress.com/Genetics/article/58/fulltext.html

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