Fatty Acid Oxidation in Zebrafish Adipose Tissue Is Promoted by 1α,25(OH)2D3

Fatty Acid Oxidation in Zebrafish Adipose Tissue Is Promoted by 1α,25(OH)2D3

1α,25(OH)2D3 (vitamin D3) is crucial for mineral homeostasis in mammals, but the precise effects of 1α,25(OH)2D3 in adipose tissue remain to be clarified in vivo. The initial 25-hydroxylation is catalyzed by liver microsomal cytochrome P450 2R1 (CYP2R1), which is conserved in vertebrates. To probe t...

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Bibliographic Details
Main Authors: Xuyan Peng, Guohui Shang, Wenqing Wang, Xiaowen Chen, Qiyong Lou, Gang Zhai, Dongliang Li, Zhenyu Du, Yali Ye, Xia Jin, Jiangyan He, Yi Zhang, Zhan Yin
Format: Article
Language:English
Published: Elsevier 2017-05-01
Series:Cell Reports
Subjects:
vitamin D3
zebrafish
lipid oxidation
adipose tissue
cyp2r1 depletion
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717305958

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http://www.sciencedirect.com/science/article/pii/S2211124717305958

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