Mode of Bioenergetic Metabolism during B Cell Differentiation in the Intestine Determines the Distinct Requirement for Vitamin B1

Bioenergetic metabolism varies during cell differentiation, but details of B cell metabolism remain unclear. Here, we show the metabolic changes during B cell differentiation in the intestine, where B cells differentiate into IgA+ plasma cells (PCs). Naive B cells in the Peyer’s patches (PPs) and Ig...

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Bibliographic Details
Main Authors: Jun Kunisawa, Yuki Sugiura, Taichi Wake, Takahiro Nagatake, Hidehiko Suzuki, Risa Nagasawa, Shiori Shikata, Kurara Honda, Eri Hashimoto, Yuji Suzuki, Mitsutoshi Setou, Makoto Suematsu, Hiroshi Kiyono
Format: Article
Language:English
Published: Elsevier 2015-10-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124715009602