Synthetic emmprin peptides with chitobiose substitution stimulate MMP-2 production by fibroblasts

Synthetic emmprin peptides with chitobiose substitution stimulate MMP-2 production by fibroblasts

<p>Abstract</p> <p>Background</p> <p>Emmprin, a glycoprotein containing two Ig domains, is enriched on tumor cell surfaces and stimulates matrix metalloproteinase (MMP) production by adjacent stromal cells. Its first Ig domain (ECI) contains the biologically active site...

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Bibliographic Details
Main Authors: Suzumiya Junji, Toole Bryan P, Nakahara Yoshiaki, Koga Kaori, Hojo Hironobu, Sameshima Tetsuro, Kawakami Takehito, Okada Yasunori, Iwasaki Akinori, Nabeshima Kazuki
Format: Article
Language:English
Published: BMC 2011-07-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/11/300

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http://www.biomedcentral.com/1471-2407/11/300

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