Heme oxygenase 1 is associated with ischemic preconditioning-induced protection against brain ischemia

Ischemic preconditioning (IPC) protects brain against ischemic injury by activating specific mechanisms. Our goal was to determine if the inducible heme oxygenase 1 (HO1) is required for such protection. IPC before transient or permanent ischemia reduced cortical infarct volumes by 57.4% and 33.9%,...

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Bibliographic Details
Main Authors: Emil Zeynalov, Zahoor A. Shah, Rung-chi Li, Sylvain Doré
Format: Article
Language:English
Published: Elsevier 2009-08-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996109001041