Probing the Structure–Function relationship and amyloidogenic propensities in natural variants of apolipoprotein A-I

Probing the Structure–Function relationship and amyloidogenic propensities in natural variants of apolipoprotein A-I

Background: Apolipoprotein A-I (apoA-I) protects against atherosclerosis and participates in the removal of excess cellular cholesterol from peripheral organs. Several naturally occurring apoA-I mutations are associated with familial systemic amyloidosis, with deposition of amyloid aggregates in per...

Full description

Bibliographic Details
Main Authors: Farah Ma'arfi, Subhash Chandra Prasad, Jamal e Fatima, Mohd Yasir Khan, Snober S. Mir, Mohd Aslam Yusuf
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Biochemistry and Biophysics Reports
Subjects:
Apolipoprotein A-I
Mutation
Amyloid
Atherosclerosis
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580820301254

Internet

http://www.sciencedirect.com/science/article/pii/S2405580820301254

Similar Items