miR-181a-5p Regulates TNF-α and miR-21a-5p Influences Gualynate-Binding Protein 5 and IL-10 Expression in Macrophages Affecting Host Control of Brucella abortus Infection

miR-181a-5p Regulates TNF-α and miR-21a-5p Influences Gualynate-Binding Protein 5 and IL-10 Expression in Macrophages Affecting Host Control of Brucella abortus Infection

Brucella abortus is a Gram-negative intracellular bacterium that causes a worldwide zoonosis termed brucellosis, which is characterized as a debilitating infection with serious clinical manifestations leading to severe complications. In spite of great advances in studies involving host–B. abortus in...

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Bibliographic Details
Main Authors: Patrícia P. Corsetti, Leonardo A. de Almeida, André Nicolau Aquime Gonçalves, Marco Túlio R. Gomes, Erika S. Guimarães, João T. Marques, Sergio C. Oliveira
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Immunology
Subjects:
microRNA
epigenetics
Brucella abortus
guanylate-binding protein 5
inflammation
miR-21a-5p
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01331/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.01331/full

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