Differential In Vitro Cultivation of Francisella tularensis Influences Live Vaccine Protective Efficacy by Altering the Immune Response

Differential In Vitro Cultivation of Francisella tularensis Influences Live Vaccine Protective Efficacy by Altering the Immune Response

Francisella tularensis (Ft) is a biothreat agent for which there is no FDA-approved human vaccine. Currently, there are substantial efforts underway to develop both vaccines and improved tools to assess these vaccines. Ft expresses distinct sets of antigens (Ags) in vivo as compared to those express...

Full description

Bibliographic Details
Main Authors: Raju Sunagar, Sudeep Kumar, Sarah J. Rosa, Karsten R. O. Hazlett, Edmund J. Gosselin
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Immunology
Subjects:
Francisella tularensis
live vaccine
brain hear infusion medium
biodefense
mucosal vaccines
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01594/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.01594/full

Similar Items