Synthesis of N-Methyl-6-heterocyclic-1-oxoisoindoline Derivatives by Microwave Assisted Buchwald-Hartwig Amination
An rapid and efficient microwave assisted Pd(II) catalyzed protocol for the preparation of N-methyl-6-heterocyclic-1-oxoisoindoline derivatives by Buchwald-Hartwig amination with an overall yield 68-85% has been described.
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2011-01-01
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Series: | E-Journal of Chemistry |
Online Access: | http://dx.doi.org/10.1155/2011/851935 |