Stage-specific role of interferon-gamma in experimental autoimmune encephalomyelitis and multiple sclerosis

The role of interferon-γ (IFN-γ) in multiple sclerosis (MS) and its animal model experimental autoimmune encephalomyelitis (EAE) has remained as an enigmatic paradox for more than 30 years. Several studies attribute this cytokine a prominent proinflammatory and pathogenic function in these pathologi...

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Bibliographic Details
Main Authors: Gabriel eArellano, Payton Amelia Ottum, Lilian eReyes, Paula eBurgos, Rodrigo eNaves
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-09-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00492/full