Stage-specific role of interferon-gamma in experimental autoimmune encephalomyelitis and multiple sclerosis
The role of interferon-γ (IFN-γ) in multiple sclerosis (MS) and its animal model experimental autoimmune encephalomyelitis (EAE) has remained as an enigmatic paradox for more than 30 years. Several studies attribute this cytokine a prominent proinflammatory and pathogenic function in these pathologi...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2015-09-01
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Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00492/full |