Longitudinal characterization of HIV-1 pol-gene in treatment-naïve men-who-have-sex-with-men from acute to chronic infection stages

Longitudinal characterization of HIV-1 pol-gene in treatment-naïve men-who-have-sex-with-men from acute to chronic infection stages

HIV-1 is characterized by its ability to mutate and recombine even at polymerase (pol) gene. However, pol-gene diversity is limited due to functional constraints. The aim of this study was to characterize longitudinally, by next-generation sequencing (NGS), HIV-1 variants based on pol-gene sequences...

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Bibliographic Details
Main Authors: Cintia Cevallos, Andrés C.A. Culasso, Carlos Modenutti, Ana Gun, Omar Sued, María M. Avila, Diego Flichman, M. Victoria Delpino, Jorge Quarleri
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Heliyon
Subjects:
Genetics
Microbiology
Virology
Viruses
Viral disease
Viral genetics
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844020325226

Internet

http://www.sciencedirect.com/science/article/pii/S2405844020325226

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