Early fibrinogen concentrate therapy for major haemorrhage in trauma (E-FIT 1): results from a UK multi-centre, randomised, double blind, placebo-controlled pilot trial

Early fibrinogen concentrate therapy for major haemorrhage in trauma (E-FIT 1): results from a UK multi-centre, randomised, double blind, placebo-controlled pilot trial

Abstract Background There is increasing interest in the timely administration of concentrated sources of fibrinogen to patients with major traumatic bleeding. Following evaluation of early cryoprecipitate in the CRYOSTAT 1 trial, we explored the use of fibrinogen concentrate, which may have advantag...

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Bibliographic Details
Main Authors: Nicola Curry, Claire Foley, Henna Wong, Ana Mora, Elinor Curnow, Agne Zarankaite, Renate Hodge, Valerie Hopkins, Alison Deary, James Ray, Phil Moss, Matthew J. Reed, Suzanne Kellett, Ross Davenport, Simon Stanworth
Format: Article
Language:English
Published: BMC 2018-06-01
Series:Critical Care
Subjects:
Fibrinogen replacement therapy
Haemorrhagic shock
Multiple trauma
Cryoprecipitate
Transfusion
Online Access:http://link.springer.com/article/10.1186/s13054-018-2086-x

Internet

http://link.springer.com/article/10.1186/s13054-018-2086-x

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