The Metabolic Requirements of Th2 Cell Differentiation

Upon activation, naïve CD4+ T cells differentiate into a number of specialized T helper (Th) cell subsets. Th2 cells are central players in immunity to helminths and are implicated in mediating the inflammatory pathology associated with allergies. The differentiation of Th2 cells is dependent on tra...

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Bibliographic Details
Main Authors: Julian M. Stark, Christopher A. Tibbitt, Jonathan M. Coquet
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Immunology
Subjects:
Th2
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02318/full