Effect of Histone Deacetylase Inhibition on the Expression of Multidrug Resistance-associated Protein 2 in a Human Placental Trophoblast Cell Line

Effect of Histone Deacetylase Inhibition on the Expression of Multidrug Resistance-associated Protein 2 in a Human Placental Trophoblast Cell Line

Background: Placental multidrug resistance-associated protein 2 (MRP2), encoded by ABCC2 gene in human, plays a significant role in regulating drugs' transplacental transfer rates. Studies on placental MRP2 regulation could provide more therapeutic targets for individualized and safe pharmacoth...

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Bibliographic Details
Main Authors: Hong-Yu Duan, Dan Ma, Kai-Yu Zhou, Tao Wang, Yi Zhang, Yi-Fei Li, Jin-Lin Wu, Yi-Min Hua, Chuan Wang
Format: Article
Language:English
Published: Wolters Kluwer 2017-01-01
Series:Chinese Medical Journal
Subjects:
Epigenetic Regulation; Histone Deacetylases; Multidrug Resistance-associated Protein 2; Placenta
Online Access:http://www.cmj.org/article.asp?issn=0366-6999;year=2017;volume=130;issue=11;spage=1352;epage=1360;aulast=Duan

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http://www.cmj.org/article.asp?issn=0366-6999;year=2017;volume=130;issue=11;spage=1352;epage=1360;aulast=Duan

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