Cytotoxic effects of Clusterin antisense oligonucleotides and Docetaxel on two prostate cancer cell lines

Background: Clusterin is a glycoprotein that is overexpressed under stress conditions and causes cell survival by inhibiting apoptosis. Clusterin is overexpressed in prostate cancer. Antisense RNA drugs bind to mRNA of target gene and lead to inhibition of protein translation. Objective: The aim of...

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Bibliographic Details
Main Authors: N. Bakhtiari, SM. Safavi, K. Hoseinipajouh
Format: Article
Language:fas
Published: Qazvin University of Medical Sciences & Health Services 2015-06-01
Series:The Journal of Qazvin University of Medical Sciences
Subjects:
Online Access:http://journal.qums.ac.ir/browse.php?a_id=1788&slc_lang=en&sid=1&ftxt=1