Combining controls can improve power in two-stage association studies
Abstract Background High dimensional case control studies are ubiquitous in the biological sciences, particularly genomics. To maximise power while constraining cost and to minimise type-1 error rates, researchers typically seek to replicate findings in a second experiment on independent cohorts bef...
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| Format: | Article |
| Language: | English |
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BMC
2018-10-01
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| Series: | BMC Genetics |
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| Online Access: | http://link.springer.com/article/10.1186/s12863-018-0675-y |