Preclinical evaluation of KIT/PDGFRA and mTOR inhibitors in gastrointestinal stromal tumors using small animal FDG PET

Preclinical evaluation of KIT/PDGFRA and mTOR inhibitors in gastrointestinal stromal tumors using small animal FDG PET

<p>Abstract</p> <p>Background</p> <p>Primary and secondary drug resistance to imatinib and sunitinib in patients with gastrointestinal stromal tumors (GISTs) has led to a pressing need for new therapeutic strategies such as drug combinations. Most GISTs are caused by mu...

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Bibliographic Details
Main Authors: Fanti Stefano, Castellucci Paolo, Di Battista Monica, Nannini Margherita, Boschi Stefano, Quarta Carmelo, Gnocchi Chiara, Landuzzi Lorena, Nanni Cristina, Nicoletti Giordano, Pantaleo Maria, Lollini Pier, Bellan Elena, Castelli Mauro, Rubello Domenico, Biasco Guido
Format: Article
Language:English
Published: BMC 2010-12-01
Series:Journal of Experimental & Clinical Cancer Research
Online Access:http://www.jeccr.com/content/29/1/173

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http://www.jeccr.com/content/29/1/173

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