Embryonic Cells Redistribute SUMO1 upon Forced SUMO1 Overexpression

Embryonic stem (ES) cells exhibit unusual transcriptional, proteomic, and signal response profiles, reflecting their unusual needs for rapid differentiation and replication. The work reported here demonstrated that mouse embryonic cell lines did not tolerate the overexpression of SUMO1, the small ub...

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Bibliographic Details
Main Authors: Andreia Lee, Yiping Zhu, Yosef Sabo, Stephen P. Goff
Format: Article
Language:English
Published: American Society for Microbiology 2019-12-01
Series:mBio
Subjects:
Online Access:https://doi.org/10.1128/mBio.01856-19