Autoantibody of NRIP, a novel AChR‐interacting protein, plays a detrimental role in myasthenia gravis

Autoantibody of NRIP, a novel AChR‐interacting protein, plays a detrimental role in myasthenia gravis

Abstract Background Nuclear receptor interaction protein (NRIP) co‐localizes with acetylcholine receptor (AChR) at the neuromuscular junction (NMJ), and NRIP deficiency causes aberrant NMJ architecture. However, the normal physiological and pathophysiological roles of NRIP in NMJ are still unclear....

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Bibliographic Details
Main Authors: Li‐Kai Tsai, I‐Hsin Chen, Chi‐Chao Chao, Hsueh‐Wen Hsueh, Hsin‐Hsiung Chen, Yun‐Hsin Huang, Rong‐Wei Weng, Tzu‐Yun Lai, Yi‐Chieh Tsai, Yeou‐Ping Tsao, Show‐Li Chen
Format: Article
Language:English
Published: Wiley 2021-06-01
Series:Journal of Cachexia, Sarcopenia and Muscle
Subjects:
Autoantibody; Acetylcholine receptor; Myasthenia gravis; Neuromuscular junction; Nuclear receptor interaction protein
Online Access:https://doi.org/10.1002/jcsm.12697

Internet

https://doi.org/10.1002/jcsm.12697

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