Targeting LRH-1/NR5A2 to treat type 1 diabetes mellitus

Targeting LRH-1/NR5A2 to treat type 1 diabetes mellitus

Type 1 diabetes mellitus (T1DM) is defined as an autoimmune disease that targets the selective destruction of islet insulin-producing beta cells by infiltrating immune cells (insulitis). As a result, the organism is no longer able to produce insulin and develops hyperglycaemia and, if untreated, dea...

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Bibliographic Details
Main Authors: Nadia Cobo-Vuilleumier, Petra I. Lorenzo, Benoit R. Gauthier
Format: Article
Language:English
Published: Shared Science Publishers OG 2018-05-01
Series:Cell Stress
Subjects:
LRH-1
NR5A2
immune tolerance
islet regeneration
trans-differentiation
therapy
Online Access:http://www.cell-stress.com/researcharticles/targeting-lrh-1-nr5a2-to-treat-type-1-diabetes-mellitus/

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http://www.cell-stress.com/researcharticles/targeting-lrh-1-nr5a2-to-treat-type-1-diabetes-mellitus/

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