Smoking-induced control of miR-133a-3p alters the expression of EGFR and HuR in HPV-infected oropharyngeal cancer.

PURPOSE:Human papillomavirus (HPV) infected oropharyngeal squamous cell carcinoma (OPSCC) patients have a better prognosis compared to HPV(-) counterparts. However, a subset of HPV(+) patients with a smoking history fail to respond to the standard of care treatments such as radiation and chemotherap...

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Main Authors: Reniqua House, Mrinmoyee Majumder, Harinarayan Janakiraman, Besim Ogretmen, Masanari Kato, Evren Erkul, Elizabeth Hill, Carl Atkinson, Jeremy Barth, Terrence A Day, Viswanathan Palanisamy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6173415?pdf=render