In vivo chemical reprogramming of astrocytes into neurons

Abstract In mammals, many organs lack robust regenerative abilities. Lost cells in impaired tissue could potentially be compensated by converting nearby cells in situ through in vivo reprogramming. Small molecule-induced cell reprogramming offers a temporally flexible and non-integrative strategy fo...

Full description

Bibliographic Details
Main Authors: Yantao Ma, Handan Xie, Xiaomin Du, Lipeng Wang, Xueqin Jin, Qianqian Zhang, Yawen Han, Shicheng Sun, Longteng Wang, Xiang Li, Changjiang Zhang, Mengdi Wang, Cheng Li, Jun Xu, Zhuo Huang, Xiaoqun Wang, Zhen Chai, Hongkui Deng
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Cell Discovery
Online Access:https://doi.org/10.1038/s41421-021-00243-8